Gene Mutations Within Glioblastoma Research

By Rob Sutter


If you have been involved in glioblastoma research in some way or another, you know all about the condition at hand. Gliomas are viewed as some of the most common, not to mention most severe, tumors seen in the brain and this is why research seems to focus on them in particular. That being said, what can be done in order to help the matter that much more? After reading up on the matter, it seems like there may be a new relation of sorts.

BioNews Texas wrote an article concerning the number of findings that have been made in the way of glioblastoma multiforme. To say that researchers have focused on the matter would be an understatement, as the report made mention of how 23,000 cases are expected in this year alone. Keep in mind that a patient can be given a 15-month diagnosis. It's clear that there is work to be done on the matter and there have been multiple findings that could prove to be useful in this field.

Lynda Chin, M.D. - who is not only a professor at the Cancer Genome Atlas but its chair as well - has talked about a series of findings. They came to the surface following a five-year sojourn and I'd like to think that such findings can prove to be useful in time. After all, the information in question referred to factors like genetic mutations, deletions, and others which one would correlate these tumors. It's just a matter of incorporating such information so that therapies can be made with more effectiveness.

I believe that past mutations have to be looked to as well, a point that is supported by organizations along the lines of Voices against Brain Cancer. Keep in mind that there are many individuals who have been involved in the realm of glioblastoma research and they can tell you about the many findings related to genes. The report said that 61 mutated genes have been newly discovered and one of the more interesting points of information had to do with the epidermal growth factor receptor. For those who do not know, the EGFR gene was seen as mutated in 57% of these tumors.

Considering all of the work that has been seen glioblastoma research so far, it's clear that these particular tumors have been given tremendous attention. They are some of the most complicated growths you can imagine and they are going to vary in many ways from one patient to the next. The ability to pinpoint certain genes, though, can lend a greater assist to the methods conducted in the way of research. My only hope is that this kind of information will make therapies in place even better.




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